“This is an allergic disease, and allergists need to help take care of this person.”

– Dr. Seema Aceves

Found yourself scratching your head about how to approach EoE in young patients? Who will go on to develop chronic disease, facing stricture and food impaction from remodelling? Our current approach can feel like it is stuck in the Stone Age. But not to worry, Dr. Seema Aceves will rocket us to the cutting edge of EoE diagnostics and treatment.

Dr. Seema Aceves is Professor of Pediatrics and Medicine at the University of California, San Diego, and Rady Children’s Hospital. She directs the Eosinophilic Gastrointestinal Disorders Clinic and leads an NIH- and CURED-funded research program focused on the mechanisms and clinical impact of tissue remodelling in eosinophilic esophagitis.

On this episode, they discuss:

• EoE is a type 2 inflammatory disease, and allergists need to help treat it.
• How remodelling happens when EoE persists.
• Between 95 and 99 per cent of patients have chronic disease.
• The limits of eosinophils as a biomarker.
• Where gastroenterologists fit into EoE care, and where they don’t.
• OIT causes EoE in 4 to 5 per cent of cases.
• The role of elimination diets in treating EoE.
• Emerging tools to identify which patients will develop remodelling.

Dr. Aceves keeps returning to one idea: this disease starts early and builds quietly, and allergists have a key role in detecting its advance in time to prevent strictures.

Posted on September 29, 2026.